BLUEHYS MED

Research for the clinical innovation.

BlueHyS Med brings a proprietary technology, developed through research, clinical studies and medical innovation, into everyday clinical practice. A platform designed to support the work of healthcare professionals with a non-invasive, safe approach grounded in ongoing scientific validation.

RESEARCH AND SCIENTIFIC VALIDATION

Clinical Validation

Innovation in medicine takes much more than a good idea: it takes research, evidence and an ongoing validation process. BlueHyS Med was born from this approach, with the aim of turning proprietary technology into a practical tool supporting clinical practice.


Scientific research

The BlueHyS Method builds on the study of molecular hydrogen and its role in modulating oxidative stress and inflammatory processes.

Patented technology

The BlueHyS platform is protected by an intellectual property structure that includes an international patent application (PCT) and an Italian application.

The experience

A session of just 20 minutes to reset oxidative stress and stimulate mitochondrial vitality.

THE METHOD

Innovation that supports clinical practice

BlueHyS Med is based on a patented proprietary technology that combines molecular hydrogen and a blend of essential micronutrients through a non-invasive transdermal protocol. The method was developed to promote systemic bioavailability of hydrogen and to fit into clinical practice as a support to therapeutic and care pathways.

Ongoing research

At the heart of the BlueHyS Method is a platform developed to deliver molecular hydrogen through the skin, without invasive procedures, enhancing the role of the proprietary blend of micronutrients.

Ricercatrice studia il potenziale anti-infiammatorio delle soluzioni BlueHyS med

Non-invasive protocol

The treatment involves immersing hands and feet in warm water enriched with micronutrients. A simple, standardised and customisable protocol, designed to fit easily into clinical practice.

Mani bagnate illustrano il trattamento transdermico BlueHyS per la vitalità

Non-invasive transdermal delivery

Paziente rassicurata dall'approccio non invasivo e anti-ossidativo di BlueHyS

The treatment in detail

Consulto in studio per integrare il trattamento clinico BlueHyS med
STEP 1

Assessment and personalisation

Every treatment begins with an assessment of the person’s needs, to define a protocol tailored to the clinical context and the goals of the programme.

Mano in acqua: esperienza rilassante del trattamento anti-infiammatorio BlueHyS
STEP 2

The treatment

For about 20-30 minutes, hands and feet are immersed in warm water (37-42 °C) enriched with a blend of essential micronutrients, while the device generates molecular hydrogen using BlueHyS proprietary technology. The treatment is non-invasive, simple and comfortable.

Supporto medico-paziente nel percorso per ritrovare vitalità con BlueHyS
STEP 3

Integration into clinical practice

Thanks to its standardised and customisable protocol, the BlueHyS Method is designed to fit easily into care pathways, supporting the work of healthcare professionals.

FIELDS OF APPLICATION

Where BlueHyS Med can make a difference


Oncology

The BlueHyS Method is the subject of studies on supporting the wellbeing and quality of life of oncology patients, alongside their treatment pathways.

Regenerative medicine

BlueHyS research explores the potential of molecular hydrogen to support biological processes involved in maintaining cellular and tissue balance.

Orthopaedics

An application focused on recovery and on supporting the physiological processes involved in rehabilitation and post-operative pathways.

Clinical research

A programme of studies and partnerships with universities and research centres aimed at expanding the scientific evidence and future applications of the BlueHyS Method.

Clinical impact and safety

The BlueHyS Method is the result of a research and validation process aimed at ensuring a safe, non-invasive approach that integrates easily into clinical practice. The technology is supported by studies, partnerships with universities and research centres, and a development strategy focused on expanding the scientific evidence and potential clinical applications.

Medico al computer analizza i dati della metodologia BlueHyS med

Clinical Research

BlueHyS runs a scientific research programme aimed at generating clinical evidence on the use of molecular hydrogen delivered through the BlueHyS Method. Research activities are carried out in partnership with universities, IRCCS research hospitals and leading clinical centres in Italy and abroad, with the aim of validating the device across different fields of application through clinical and preclinical studies.

Evaluation of the feasibility, safety and efficacy of the BlueHyS Method as a support to cancer treatments.

Study site

IRCCS Policlinico Sant’Orsola, University of Bologna

Principal Investigator

Prof. Giovanni Brandi

Study design

Exploratory, single-centre, post-marketing, open-label pilot study including healthy volunteers and cancer patients undergoing chemotherapy or tyrosine kinase inhibitor therapy.

Objectives

To assess the safety of the treatment and the potential role of the BlueHyS Method in preventing and recovering from toxicity related to cancer therapies.

Main results
  • No device-related adverse events.
  • Reduction in oxidative stress.
  • Improvement in quality-of-life parameters.
  • Preliminary signs of reduced toxicity from cancer treatment.
  • Case series showing improvement in peripheral neuropathy and chemotherapy-induced alopecia.
Status

Analysis completed; scientific manuscript in the publication process

Evaluation of the efficacy of the BlueHyS Method in knee osteoarthritis.

Study site

IRCCS Istituto Ortopedico Rizzoli, Bologna

Principal Investigator

Prof. Stefano Zaffagnini

Study design

Randomised, placebo-controlled clinical study in 220 patients with knee osteoarthritis.

Objective

To assess the efficacy of the BlueHyS Method as a complementary, drug-free treatment for managing knee osteoarthritis.

Primary endpoints
  • Pain reduction (WOMAC Pain)
  • Joint function
  • Quality of life (SF-36)
  • Pain (VAS)
  • Oxidative stress biomarkers

Research that continues to evolve

The BlueHyS Method continues to develop through ongoing intellectual property protection, scientific research and clinical validation, with the aim of strengthening the evidence behind it and broadening its applications.

INTELLECTUAL PROPERTY

A protected technology

BlueHyS holds an international patent application (PCT/EP2023/058095) and an Italian patent application (IT102023000020361), protecting its proprietary technology and its future development.

CLINICAL STUDIES

Research reaches clinical practice

The BlueHyS Method has been the subject of pilot studies in oncology at the Policlinico Sant’Orsola-Malpighi in Bologna and assessments focused on sports recovery, with the aim of further investigating its safety, tolerability and potential applications.

SCIENTIFIC VALIDATION

Research that continues

The BlueHyS platform continues to develop through partnerships with universities and research centres, and an ongoing programme of scientific studies and publications on molecular hydrogen and its applications.

Contacts

Every collaboration begins with a conversation. If you’d like to learn more about the BlueHyS Method, explore its applications, or receive more information, fill out the form: our team will be happy to assist you.